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There is increasing evidence for an association of short‐term exposure to particulate matter (PM) with elevated risk of cardiovascular disease, including stroke.1, 2, 3 Stroke is listed as the second leading cause of death in the Global Burden of Disease 2010, and the incidence of stroke is increasing, particularly in low‐ and middle‐income countries, which account for two‐thirds of all strokes.4, 5 To enhance primary prevention efforts, the relationship of PM with stroke requires further investigation given the high stroke burden in terms of mortality and disability worldwide.Previous reports examining the effect of PM on stroke have shown inconsistent results.1, 6, 7, 8 Moreover, toxicological studies suggest that fine particles may be more harmful to the circulation system than coarse particles.9 Indeed, coarse particles are mostly deposited in the upper respiratory tract, whereas fine particles can be inhaled deep into the lung and translocated via the circulation to other organs.10, 11 However, only limited epidemiological studies have examined the relationship between stroke and PM of different particle sizes.1, 12, 13Regarding the various subtypes of stroke, most prior reports have focused on cerebrovascular disease or ischemic stroke, while a few studies have examined ischemic and hemorrhagic stroke separately but reported inconsistent results.12, 14, 15 Further, some studies reported that the risk of stroke associated with air pollution differed by ambient temperature or season, although there are contrasting findings.16, 17, 18, 19 Additionalr studies are therefore required to improve our understanding of the biological mechanism of the association and develop specific interventions for specific groups and days.The aims of this study were to examine the association of PM with stroke admissions in Beijing, China, during 2013–2014 and to determine whether the association differed across particle size, stroke subtype, patient characteristics, and ambient temperature, by using a time‐stratified case‐crossover design.), were obtained from the Centre of City Environmental Protection Monitoring Website Platform ( from January 1, 2013, through December 31, 2014, in Beijing.There were 35 monitoring stations located in 16 districts of Beijing.Background The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature.We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013–2014.Daily data for stroke admissions from January 1, 2013, through December 31, 2014, were obtained from the medical record database for cardiovascular and cerebrovascular disease in Beijing.

For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658–2.273), 1.590 (95% CI 1.366–1.851), and 1.527 (95% CI 1.278–1.826).The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C).



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The growing acceptance of the value of excavating Post-Medieval deposits and the increased amount of rescue archaeology, particularly in urban settings, led to an exponential increase in clay pipe studies.… continue reading »


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