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Inside the red blood cell, the Babesia organism divests its outer coating and begins to divide, becoming a new form called a “merozoite” which a new tick may ingest during a blood meal." "Following ingestion by the tick, Babesia undergoes sexual reproduction (gamogony) followed by asexual reproduction (often schizogony and always sporogony), resulting in numerous sporozoites (in the tick salivary glands) that are infective to vertebrate hosts." Pregnant dogs can give Babesia canis to their unborn puppies and it is recommended that infected females should not be bred.The clinical signs of Babesia canis are lethargy, weakness, vomiting, anorexia, fever, pale mucous membranes, and dark discoloration of the urine.While only certain laboratories run this type of testing, this is really the best method." "Dogs infected with Babesia canis usually respond to treatment with imidocarb dipropionate at a dose of 6 mg/kg IM administered twice at 14-day intervals.A higher dose administered once is recommended occasionally but can result in neurotoxicity.
There may be other symptoms including neurological and respiratory signs. A veterinarian can take a blood smear, but the odds of being able to see the parasite is unlikely as it is small.If the veterinarian wants to take blood, it is best to take it from a capillary source (such as a fresh cut) than from a blood vessel.