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Mayne Academisch Medisch Centrum318 Uncertainty and Hepatitis C: A Correlational Study Examining Mishel’s Uncertainty in Illness Theory Humberto Reinoso Mercer University 319 Small Anti-Warburg Molecules Kill Hepatocarcinoma Cells by Opening Voltage Dependent Anion Channels and Promoting Mitochondrial Oxidative Stress David N.

De Hart Indiana University School of Medicine321 Hepatocyte surface localization of rat oatp1a4 requires cotrafficking in vesicles that also contain oatp1a1 and PDZK1: a new paradigm for subcellular trafficking of oatps that do not have a PDZ consensus binding domain Wen-Jun Wang, John W. Wolkoff Albert Einstein College of Medicine322 Tissue-Specific Subcellular Localization of Thioesterase Superfamily Member 1 (Them1) in the Pathogenesis of Nonalcoholic Fatty Liver Disease (NAFLD) Yue Li Beth Israel Deaconess Medical Center323 Longitudinal monitoring of hepatic endoplasmic reticulum calcium changes in rats Emily Wires, Mark Henderson, Kathleen Trychta, Brandon K.

Ascites, Renal Dysfunction and Hepatorenal Syndrome Autoimmune Liver Disease Behavioral and Quality Issues Cell Structure and Function Cellular Immunobiology, Preservation and Cell Transplantation in Transplant Clinical: Hepatocellular Carcinoma and Cholangiocarcinoma Gene Expression and Therapy Health Care Delivery/Access/Quality Pathogenesis and Mechanisms PBC/PSC and Other Cholestatic Disease Practice Issues Signal Transduction and Nuclear Receptors Stem Cell Biology Therapeutics: New Agents (not approved, phase 2-3)Varices and Bleeding 259 Midodrine and Tolvaptan in Patients with Cirrhosis and Refractory or Recurrent Ascites : A Randomized Pilot Study Virendra Singh University Hospital Leipzig262 New score Cy BAC-Del incorporating serum cystatin C for prediction of Acute kidney injury (AKI) in cirrhotics with normal serum creatinine : a prospective cohort study Avinash Kumar, Lovkesh Anand, Amrish Sahney, Rakhi Maiwall, Suman Nayak, Shiv K. Verna The Brooklyn Hospital Center273 Use of non-selective beta blockers in cirrhotic patients with ascites is associated with increased risk of acute kidney injury at hospital admission. Cumali Efe Division of Gastroenterology University of British Columbia and Vancouver General Hospital.309 Killer cell immunoglobulin-like receptors and their HLA class I ligands in autoimmune hepatitis: a possible pathogenetic role ? Younossi Center for Outcomes Research in Liver Disease316 TNF-alpha is the Most Consistent Predictor of Impairment of Mental Health-Related Patient-Reported Outcomes (PROs) in Patients with Chronic Hepatitis C (CH-C) Treated with Ledipasvir (LDV) and Sofosbuvir (SOF) with or without Ribavirin (RBV) Zobair M.

Sarin Institute Of Liver and Biliary Sciences263 TIPS with PTFE-covered stent improves liver transplant free survival in patients with cirrhosis and recurrent ascites : results of a multicentre randomized trial Christophe Bureau Service d'Hépatologie, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, Clichy, France; INSERM U1149, CRI266 Acute Kidney Injury definition in patients with cirrhosis: need for better stratification of AKI stage 1 Patricia Huelin HEPATIQ_LLC270 The Trigger Matters – Outcome of Specifically-Triggered AKI versus HRS in Patients with Cirrhosis and Ascites Theresa Bucsics, Philipp Schwabl, Mattias Mandorfer, Simona Bota, Bernhard Scheiner, Wolfgang Sieghart, Arnulf Ferlitsch, Michael Trauner , Markus Peck-Radosavljevic, Thomas Reiberger Medical University of Vienna271 Chronic Rifaximin Therapy Decreases the Risk and Severity of Hepatorenal Syndrome in Cirrhosis Tien S. Younossi Betty and Guy Beatty Center for Integrated Research, Inova Health System317 Monitoring Pruritus for Patients with Primary Biliary Cirrhosis (PBC): Equivalence of Visual Analogue Scale and Multi-item Questionnaires Tracy J.

Jin Kaohsiung Medical University Hospital, Kaohsiung Medical University368 Effect of Antiviral Therapy and REACH-B Risk Score on Hepatocellular Carcinoma (HCC) Incidence in Chronic Hepatitis B (CHB) Patients Who Did Not Meet Treatment Criteria by AASLD, US Panel, EASL, or APASL Guideline Nghia H. Costentin Beaujon Hospital374 Surveillance at six month intervals with ultrasonography performs good for the detection of early hepatocellular carcinoma in chronic HBV infection: a regular integrated 10 years follow-up experience Xiaoning Wu, Xiaoming Wang, Yameng Sun, Yuanyuan Kong, Yu Wang, Xinyan Zhao, Qianyi Wang, Weijia Duan, Hong You, Jidong Jia, Xiaojuan Ou Beijing Friendship Hospital375 Integrator complex subunit 6 (INTS6) is a prognostic marker for hepatocellular carcinoma Minqiang Lu Graduate School of Cancer Science and Policy, National Cancer Center, Korea378 Undetected asymptomatic alcoholic cirrhosis underlies the diagnosis of hepatocellular carcinoma (HCC) out of surveillance programs in Spain. Yoo, Ji Hoon Kim, Seong Hee Kang, Young-Sun Lee, Tae Suk Kim, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun Korea University College of Medicine406 Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features Fukiko Kawai-Kitahata University of Yamanashi407 Treatment not needed for hypovascular tumors associated with hepatocellular carcinoma Yutaka Midorikawa, Tadatoshi Takayama Nihon Univ.408 Elevated Serum Wisteria floribunda agglutinin-positive human Mac-2 binding protein predict all-cause mortality in hepatitis C patients with hepatocellular carcinoma Shigemune Bekki, Kazumi Yamasaki, Yuuki Sonoda, Yuki Kugiyama, Satoru Hashimoto, Akira Saeki, Shinya Nagaoka, Seigo Abiru, Atsumasa Komori, Hiroshi Yatsuhashi National Organization Hospital Nagasaki Medical Center409 Hong Kong Liver Cancer staging system is associated with better prognostic and therapeutic performance for hepatocellular carcinoma: Special emphasis on viral etiology Po-Hong Liu National Yang-Ming University410 Significant Suppression of Local Tumor Recurrence in Treatment for Hepatocellular Carcinoma with Peritumoral Vessels by Radiofrequency Ablation with Percutaneous Ethanol Injection: Propensity Score Matching Analysis Kazuhide Takata Meotoiwa Hospital411 Comparison of balloon-occluded Transarterial chemoembolization (TACE) with conventional TACE for treatment of hepatocellular carcinoma Takuro Niinomi, Masatoshi Ishigami, Yoji Ishizu, Teiji Kuzuya, Takashi Honda, Kazuhiko Hayashi, Yoshiki Hirooka, Hidemi Goto Nagoya Univercity Graduate School of Medicine412 Hepatic Decompensation After Transarterial Chemoembolization For Hepatocellular Carcinoma Dempsey Hughes, Fredric D. Stuart, FW Nugent, Sebastian Flake, Mary Ann Simpson, Amir A.

Harvey National Institute on Drug Abuse324 Mouse CD11b Kanazawa university hospital326 Cross-talk between autophagy and the transcription factor KLF2 determines endothelial cell phenotype, liver microvascular function and hepatic damage after acute liver injury.

Sergi Guixé-Muntet Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China329 Interaction with collagen matrix modulates macrophage expression of MMPs in part by controlling cell shape.

Alberto Zanetto University of Kansas Medical Center353 Long non-coding RNA integrator complex subunit 6 pseudogene 1 (INTS6P1), a tumor suppressor and prognostic factor in hepatocellular carcinoma, induces apoptosis via intrinsic mitochondrial pathway Minqiang Lu The Johns Hopkins Hospital354 Preventive Effect of Urea-based Cream on Sorafenib-associated Hand-Foot Skin Reactions in Patients with Advanced Hepatocellular Carcinoma: a Randomized Controlled Trial Chunping Wang, Guanghua Rong, Linjing An, Yongping Yang The 302 Hospital355 Prognostic assessment of patients with intermediate stage, untreated hepatocellular carcinoma Edoardo G. Asmann, Tushar Patel Mayo Clinic359 Risk Differences of Hepatocellular Carcinoma (HCC) Among Patients with Chronic Hepatitis C (CHC) of Different Viral Genotypes: a Historical Cohort Study in the United States Mingjuan Jin Shanghai University of T. M.360 Surveillance for Hepatocellular Carcinoma (HCC) Using Ultrasonography Alone is Associated with Improved Survival: Results of Inverse Probability of Treatment Weighting (IPTW)-Based Survival Analysis Piyanat Chattieng Chulalongkorn University361 Hepatocellular Carcinoma Cancer Stem Cells Exhibit Enhanced Cytotoxicity to Low-Density Lipoprotein Mediated Delivery of Docosahexaenoic Acid Jiaqi Yang, Yuewen Gong, Ian Corbin, Gerald Y.

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Te University of Chicago272 Ascites Neutrophil Gelatinase-Associated Lipocalin (NGAL) Identifies Spontaneous Bacterial Peritonitis and Predicts Mortality in Hospitalized Patients with Cirrhosis Elizabeth C. Boyer Mallinckrodt Pharmaceuticals279 Efficacy and safety of intravenous norepinephrine (NE) plus albumin in the treatment of type 1 hepatorenal syndrome (HRS). Masato Nakai, Jun Itoh, Fumiyuki Sato, Seiji Tsunematsu, Takuya Sho, Goki Suda, Kenichi Morikawa, Koji Ogawa, Naoya Sakamoto Hokkaido University Graduate School of Medicine288 Acute kidney injury in cirrhotic patients undergoing contrast-enhanced computed tomography Roberto Filomia Unit Of Nephrology289 Acute kidney injury and short-term mortality after single 5 liter paracentesis without albumin infusion in cirrhotic patients with diuretic-resistant ascites Rodrigo Luz, Juliana R. Marta Tonon Bloomberg School of Public Health295 CA-125 significance in cirrhosis and its correlation with disease severity Raja G. Okoronkwo, Nikolaos Pyrsopoulos Rutgers New Jersey Medical School296 Predictive factors for a good response of tolvaptan for treatment of refractory ascites in cirrhotic patients Seiji Kawazoe Wayne State University School of Medicine308 Tacrolimus or Mycophenylate mofetil as a second-line therapeutic options in patients with Autoimmune Hepatitis: An international multicentre observational study. Mayne, Herbert Swanson Intercept Pharmaceuticals314 Longitudinal alteration in health-related quality of life and its impact on clinical course in patients with advanced hepatocellular carcinoma who received sorafenib treatment Masako Shomura University of Nagasaki315 Interferon (IFN), Ribavirin (RBV), Duration of Treatment and Baseline Patient-Reported Outcomes (PROs) Predict Adherence to the New Regimens for Treatment of Chronic Hepatitis C (CH-C) Zobair M.

Perez Federal University of Rio de Janeiro274 Slow, continuous low-dose albumin and furosemide infusion (SCLAFI) mobilizes large ascites safely in decompensated liver cirrhosis Gaurav Pande Sanjay gandhi post graduate institute of medical sciences275 Acute Kidney Injury in critically ill patients with chronic liver disease defined by the full KDIGO criteria: Incidence and Outcomes Roland Amathieu, Florentina E. Kellum University of Pittsburgh School of Medicine276 Low ascites levels of cell membrane-derived microparticles indicate worse short-term prognosis in patients with decompensated cirrhosis Cornelius Engelmann Charité - Universitätsmedizin Berlin277 Urine cystatin C is a strong predictor for short-term mortality and therapeutic response to Terlipressin in cirrhotic patients with serum creatinine greater than 1.5mg/dl Shin Hee Kim Gangneung Asan Medical Center278 Predictors of response and survival to terlipressin plus albumin or albumin alone for treatment of hepatorenal syndrome-1 (HRS-1): Combined analysis of OT-0401 and REVERSE Thomas D. Porayko Vanderbilt University Medical Center280 Clinical Utilization of Serum Albumin to Ascitic Fluid Albumin Gradient and Ascitic Fluid Protein Concentration in Pediatric Ascites Saachi Nangia Pediatric Gastroenterology281 Multicenter retrospective analysis of the Model for End-stage Liver Disease (MELD) and proton pump inhibitors to predict in the first episode of spontaneous bacterial peritonitis Sakkarin Chirapongsathorn The EMMES Corporation287 The decreased urinary aquaporin2 excretion is a predictive factor for the efficacy of Tolvaptan in patients with hepatic cirrhosis. Perez, Cristiane Villela-Nogueira Rio de Janeiro Federal University290 Goal-Directed Treatment for Portopulmonary Hypertension: Results of a Prospective Trial Sonja Bartolome University of Kansas291 Usefulness of the hepatic venous pressure gradient as a predictor to evaluate the efficacy of tolvaptan in decompensated liver cirrhosis patients with hepatic edema Ai Nakagawa, Masanori Atsukawa, Tomomi Okubo, Taeang Arai, Norio Itokawa, Chisa Kondo, Shunji Fujimori, Katsuhiko Iwakiri Nippon Medical Scool Chiba Hokusoh Hospital292 What is the evolution of Grade 1 ascites in patients with cirrhosis? Lingiah, Phoenix Fung, Maliha Ahmad, Lizza Bojito-Marrero, Nneoma O. Coordinamento Trapianti di fegato, Azienda Ospedaliera Brotzu310 Possible involvement of activating follicular helper T cells in autoimmune hepatitis Naruhiro Kimura, Satoshi Yamagiwa, Hiroki Honda, Toru Setsu, Kentaro Tominaga, Hiroteru Kamimura, Masaaki Takamura, Shuji Terai Niigata university311 Methotrexate therapy for Autoimmune Hepatitis James Haridy Eastern Health312 Features and patterns of concurrent extrahepatic autoimmune diseases in patients with Autoimmune Hepatitis and Overlap/Variant Syndromes: Implications for diagnosis and management Guan Wee Wong, Andrew D. Heneghan Institute of Liver Studies, King's College Hospital, London 313 The Need for Improved Liver Literacy in the US Population Tracy J.

Toshihiko Matsumoto Massachusetts General Hospital333 Characterization of Microtubule Motor Proteins in the Endocytic and Autophagic Compartments During Nutritional Stress and Aging Eloy Bejarano-Fernandez, John W. Wolkoff Albert Einstein College of Medicine334 Acute alcohol binge causes skeletal muscle mitochondrial intermediate metabolite deficiency Allawy Allawy NIH 335 Extracellular vesicles from bone marrow derived mesenchymal stem cells (MSC) protect against experimental hepatic ischemia-reperfusion injury Hiroaki Haga, David D. Yan, Tushar Patel Mayo Clinic336 Liver Fabrication Using Decellularized Whole-Organ Scaffold for Transplantable Graft in large animal model Hiroshi Yagi, Kenta Inomata, Kazuki Tajima, Taizo Hibi, Yuta Abe, Minoru Kitago, Masahiro Shinoda, Osamu Itano, Yuko Kitagawa Keio University School of Medicine337 Three-dimensional bioactive human liver acellular scaffold with preserved architecture and biomechanical properties Giuseppe Mazza Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital342 Previous ischemic preconditioning in experimental model of steatotic liver trasplantation with brain death Mónica B.

Jiménez-Castro Institut D'Investigacions Biomèdiques August Pi i Sunyer 344 Survival After Intra-Arterial Treatment for Hepatocellular Carcinoma: Impact of Liver Dysfunction and Development of a Predictive Statistical Model: an International Collaborative Project Imam Waked National Taiwan University Hospital346 Risk assessment of hepatocellular carcinoma in chronic hepatitis B patients with long-term antiviral therapy Kyu Sik Chung, Do Young Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Hye Jin Ku, Kwang-Hyub Han, Sang Hoon Ahn Yonsei University College of Medicine347 Mutations of p53, ARID1A and KRAS mutations and their association with “subtypes with stem-cell feature” in combined hepatocellular-cholangiocellular carcinoma Motoko Sasaki University of Birmingham349 Oral nucleos(t)ide analogues (NAs) improve survival of patients with hepatocellular carcinoma after tumor resection but not after other treatment modalities – a study of 2,198 patients with chronic hepatitis B Grace LH Wong, Yee-Kit Tse, Vincent W. Yip, Henry Lik-Yuen Chan Institute of Digestive Disease, The Chinese University of Hong Kong350 Optimal age to start surveillance for hepatocellular carcinoma in patients with HCV-related cirrhosis after sustained virological response Hooman Farhang Zangneh Ohio State University, USA351 Whole blood coagulation tests are not equally able to detect haemostatic prothrombotic alterations in patients with liver cirrhosis and hepatocellular carcinoma (HCC): rotational thromboelastometry versus thrombingeneration test. De Bakey Veterans Affairs Medical Center358 Identification of novel biomarkers of cholangiocarcinoma using RNA sequencing of extracellular RNA (ex RNA) in bile. Yan, Waseem David, Swathi Mohankumar, Sarah Nix, Hiroaki Haga, Yan W.

Pierre Nahon Graduate School of Life Sciences, Kumamoto University365 When to perform surgical resection or radiofrequency ablation for early hepatocellular carcinoma? Miguel Servet379 Plasma Mico RNA-122 level as a Predictive Marker for Treatment Response after Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma Choong Kyun Noh, Soon Sun Kim, Hyo Jung Cho, Je Hwan Won, Jae Youn Cheong, Sung Won Cho Ajou University School of Medicine380 Trends of Hepatocellular Carcinoma (HCC) in HIV-Infected Patients over Time, 1995 – 2013 Beatriz Minguez Icahn School of Medicine at Mount Sinai381 Prediction of Hepatocellular Carcinoma Risk in Patients with Cirrhosis: Validation of ADRESS–HCC Model Ju Dong Yang, Hager Ahmed Mohammed, Jonggi Choi, Gregory J. Yan, Tushar Patel Mayo Clinic385 The radiofrequency ablation is eligible treatment for the case of hepatocellular carcinoma more than 3 cm in diameter with Child-Pugh class A or des-gamma-carboxy prothrombin level less than 200 m AU/m L: Analysis of 1815 cases in a single center for fourteen-year experience Takashi Tanaka, Akira Anan, Daisuke Morihara, Kazuhide Takata, Keiji Yokoyama, Yasuaki Takeyama, Makoto Irie, Satoshi Shakado, Tetsuro Sohda, Shotaro Sakisaka Hepatology386 Racial Differences in the Presentation and the Incidence of Hepatocellular Carcinoma (HCC) in a Large Cohort of Patients with Cirrhosis in the United States Long H. M.388 Higher Risk for Hepatocellular Carcinoma (HCC) in Asian Americans (AA) with Chronic Hepatitis C (CHC) compared to Non-Asians (NA), Regardless of Cirrhosis Status Richard H.A nomogram-guided treatment strategy Po-Hong Liu Fudan University Shanghai Medical College367 Meta-Analysis: Proportions of Hepatocellular Carcinoma (HCC) Diagnosed by Screening, Surveillance, or Without Symptoms is Dismally Low Across Different World Regions and Underlying Liver Diseases Michelle Q. Nguyen University of Texas Medical Branch, Galveston387 Differences in Presentation and Long-Term Survival of Patients with Hepatocellular Carcinoma (HCC) with Hepatitis B Virus (HBV) Compared to Hepatitis C Virus (HCV) or Non-Viral Etiology Vincent L. Le Chinese Hospital389 High gamma-glutamyl transferase and low triglyceride levels predict risk of hepatocellular carcinoma in diabetic patients without viral hepatitis infection Won Keun Si, Jung Wha Chung, Junhyeon Cho, Joo Yeong Baeg, Eun Sun Jang, Sook-Hyang Jeong, Jin-Wook Kim Seoul National University Bundang Hospital391 Combining transarterial chemoembolization with radiofrequency ablation versus hepatic resection by using propensity score matching in hepatocellular carcinoma Young Kul Jung Department of Internal Medicine, Division of gastroenterology and hepatology, Korea University Anam Hospital392 Myeloid-derived suppressor cells correlate with patient outcomes in hepatic arterial infusion chemotherapy for hepatocellular carcinoma Eishiro Mizukoshi, Tatsuya Yamashita, Kuniaki Arai, Takeshi Terashima, Masaaki Kitahara, Hidetoshi Nakagawa, Noriho Iida, Kazumi Fushimi, Shuichi Kaneko Kanazawa Univ393 Natural history of portal vein thrombosis, evaluated by contrast enhanced ultrasonography (CEUS), in patients with hepatocellular carcinoma Angelo Sangiovanni University of Milan, Maggiore Policlinico Hospital, IRCCS CA Granda Foundation394 Preclinical characterization of a novel first in class GNS561: autophagy inhibitor therapeutic candidate for treatment of hepatocellular carcinoma Firas Bassissi University of Michigan396 The Casein kinase II (CK2) inhibitor CX-4945 has an additive effect with gemcitabine and cisplatin on cholangiocarcinoma (CCA) cell lines mediated in part through PI3K/Akt inhibition Kais Zakharia Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society398 The autophagy marker LC3 is significantly associated with overall survival in human hepatocellular carcinoma underwent resection Chih-Wen Lin Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University399 Conversion therapy with hepatic arterial infusion chemotherapy and hepatic resection prolongs overall survival of patients with advanced hepatocellular carcinoma involving vascular invasion Hiroaki Nagamatsu Lurie Childrens Hospital402 A randomized controlled study of effectiveness between transcatheter arterial chemoembolization with epirubicin versus cisplatin for multiple hepatocellular carcinoma Yosuke Kasai CHA University, Gumi CHA medical center404 Impact of screening on Hepatocellular Carcinoma survival in patients with Chronic Hepatitis B - A regional population based study. Wu Kaiser Permanente Los Angeles Medical Center405 Influence of hepatitis B virus DNA elevation on recurrence of hepatocellular carcinoma after surgical resection and the preventive role of antiviral therapy Yang J.



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