Muscular dystrophy dating


05-Jun-2016 13:16

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In more than 95% of known cases, the disease is associated with contraction of the D4Z4 repeat in the 4q35 subtelomeric region of Chromosome 4.

Seminal research published in August 2010 now shows the disease requires a second mechanism, which for the first time provides a unifying theory for its underlying genetics.

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FSHD is the third most common genetic disease of skeletal muscle.

lists the prevalence as 4/100,000 Symptoms may develop in early childhood and are usually noticeable in the teenage years with 95% of affected individuals manifesting disease by age 20 years.



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