Noyes criteria endometrial dating dating vintage sewing
These critera were used in 300 sterility biopsies taken from normally menstruating women over a 3-year period.
Attention to qualitative changes in 8 morphological factors is most useful in dating the endometrial biopsy.
During the 1st week of luteal activity, attention should be focused on changes occurring in gland epithelium: gland mitosis, pseudostratification of nuclei, basal vacuolation, and secretion.
To test the validity of the dating criteria, change in basal body temperature was used to correlate endometrial dating with ovulation rather than onset of menstruation.
Of the 40 patients who had adequate temperature records, 31 (78%) ovulated as predicted allowing a +or- 1 day error, indicating that dating is a better gauge of duration of progesterone effect than predictor of onset of menses.
During the 2nd week , stromal changes (including edema), predecidual reaction, stromal mitosis, and leukocytic infiltration are the key criteria.Tissue from the fundus of the uterus gives the most reliable information.