All available antipsychotics are, on average, equally effective in treating acute psychotic symptoms but vary considerably in the amount of sedation they produce.
Sedation is especially common in elderly patients receiving antipsychotics.
Manage, don’t accept adverse ‘calming’ effect Sedation is a frequent side effect of antipsychotics, especially at relatively high doses.
Antipsychotics’ sedative effects can reduce agitation in acute psychosis and promote sleep in insomnia, but long-term sedation may: Many patients experience only mild, transient somnolence at the beginning of antipsychotic treatment, and most develop some tolerance to the sedating effects with continued administration.
Antipsychotic effects are not immediate and historically were thought to occur over several weeks.
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Compared with younger patients, older patients receiving the same doses of the same medications become more heavily sedated for longer periods of time.The resulting sedation can impair arousal levels during the day and increase the risk of falls.
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